Gatifloxacin

GATIFLOXACIN

PRODUCT IDENTIFICATION

CAS NO.

112811-59-3, 160738-57-8
180200-66-2 (sesquihydrate)

EINECS NO.

FORMULA

C₁₉H₂₂FN₃O₄

MOL WT.

375.40

H.S. CODE

2933.59.3600

TOXICITY

SYNONYMS

Gatiflo; Gatilox; Gatiquin; Gatispan; Tequin; Zymar; Zymaxid;

(±)-1-cyclopropyl-6-fluoro-1, 4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)- 4-oxo-3- quinolinecarboxylic acid; 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1- piperazinyl)-4-oxo-3-quinolinecarboxylic acid;

SMILES

n1(c2c(cc(c(c2OC)N2C[C@@H](C)NCC2)F)c(c(c1)C(=O)O)=O)C1CC1

CLASSIFICATION

Fluoroquinolone, Antibacterial, Anti-Infective 

EXTRA NOTES

fourth-generation fluoroquinolone which inhbits DNA gyrase and topoisomerase

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

white to off-white crystalline powder

MELTING POINT

182 - 185 C

pH

6.5 - 7.5

STABILITY

Stable under ordinary conditions.

SALES SPECIFICATION

APPEARANCE

white to off-white crystalline powder

IDENTIFICATION

complies 
TEST A (IR spectrum)
TEST B (UV spectrum)

ASSAY

99.0% min

MELTING POINT

181 - 185 C

LOSS ON DRYING

0.5% max

RESIDUE ON IGNITION

0.1% max

HEAVY METALS

20ppm max